Vaccine reactions. The result can be edema and the eventual sloughing of massive tissue areas. This is thought to be due to reaction at the injection site.

Systemic adverse reactions (such as urticaria, purpura hemorrhagica colic or anaphylaxis) can also occur.

It is further recommended that horses do not receive inactivated (killed) equine influenza vaccines within three weeks of international shipment.Other adverse reactions that have been associated with the administration of a vaccine include anaphylaxis and local irritation to the tissue, but these are uncommon. This can occur within seconds of vaccination and up to 15-20 minutes afterward. “No vaccine is 100% safe. ACVIM, says, “For intramuscular vaccines, the most typical reaction is local soreness. It is therefore recommended that horses do not receive any vaccination within two weeks of performance, sales, or shipment. The majority of the clinical signs are respiratory and may also include fever, edema and enlarged lymph nodes.

Join us as we interview leading equine researchers from the University of KentuckyHaving a plan in case of an adverse reaction can help your horse stay comfortable following vaccination.Adverse vaccination reactions can take many forms, from mild cases such as a stiff neck to the extreme of anaphylactic shock and death. Since vaccines stimulate an immune response, it is not uncommon for some horses to experience mild and transient side effects shortly after vaccination. Some will have concurrent mild fevers and may experience reduced appetite, usually the day following vaccination.”These nonspecific reactions can result in swelling and soreness. Systemic signs of malaise may be seen more commonly with the administration of intramuscular preparations of inactivated influenza virus vaccine than with others. If you continue to use the site, we'll assume you're okay with this. If you continue to use the site, we'll assume you're okay with this.

Wilson advises keeping the horse calm to avoid an increase in blood pressure, which could further circulate the infection.Local reactions are common and often present as stiffness at the injection site, which will resolve without complications. These side effects may include: Low-grade fever; Decreased appetite; Fatigue or decreased energy; Tenderness atthe injection site Keeping him in a bubble to protect him from disease isn’t feasible, but there are steps you can take to prevent another problem.Wilson suggests that, along with talking with your horse’s veterinarian, you try to ensure that the triggering vaccine is given at a different time than the other shots in your horse’s regime. In moderate to severe cases, particularly if the horse is vaccinated in the neck, the animal may be reluctant to move and appear uncoordinated. The OIE Expert Influenza Surveillance panel, reviews currently circulating strains and makes recommendations for strain inclusion in the vaccine products. Severe reactions at sites of injection can be particularly troublesome, requiring prolonged treatment and convalescence. For example, for one company’s influenza vaccine, a total of over 700 horses received a total of more 1400 doses, and they reported no severe systemic reactions, and swelling at the injection site in 2% of the horses. After receiving a vaccine (s) intramuscularly, some horses experience local muscular swelling and soreness or transient, self-limiting signs including fever, anorexia and lethargy. Equine influenza outbreaks occur worldwide and most often affect horses that are unvaccinated or have been vaccinated but not within the required time intervals set by regulatory bodies or vaccine manufacturers.

Will they have the right medications with which to treat the animal (almost all of which are prescription products)?”Other issues to consider when deciding whether to self-vaccinate include the knowledge needed for optimum selection of vaccines for each individual, storage and handling concerns, how to mix them, and how, when, and where they are administered. Horses that react to multivalent vaccines might benefit from pre-medication with a non-steroidal anti-inflammatory drug, administration of individual monovalent vaccines at different sites instead of using the multivalent vaccine, or from another brand of vaccine.Brad Bentz, VMD, Dipl.

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