Although the stockpiled antiviral drugs can treat existing cases of flu, a vaccine is the only way to protect people who are uninfected and halt further spread of the virus.The CDC, the only agency that possesses the virus needed to make a vaccine, says it is still "looking very intently" at a swine flu vaccine, but it has not yet given the green light to scale up production. During the swine flu (H1N1) pandemic, Serum was asked to develop a vaccine. "We're moving forward aggressively so that if a decision is made that we need to rev up production to make that vaccine, we would be ready to do so," he said.

Coronavirus has thrown a challenge before the human intelligence and a prompt, as well as effective retaliation, must come in the form of COVID-19 vaccine. These antibodies are robust enough to fight off the actual virus should an immunized person become infected. The science of vaccine development has advanced since the 2009 outbreak of H1N1 or swine flu. (But even if the CDC's seed stock of virus were to be released to vaccine makers today, it would take the companies anywhere from four to six months before the first inoculation could be ready for public use. There are two advantages of DNA and mRNA driven technologies.

At the biotech company Novavax, researchers are testing the use of virus-like particles (VLP), instead of the virus itself, to stimulate a flu immune response. 2020The Indian Express [P] Ltd. All Rights ReservedCoronavirus COVID19 vaccine update: During the swine flu (H1N1) pandemic, Serum was asked to develop a vaccine. Scientists are already racing to develop a vaccine for 2019-nCoV — a feat that experts say is technically possible, but still may not come in time to help during this outbreak. Novavax's strategy involves isolating three proteins from the virus that flag the human immune system, which then churns out neutralizing antibodies against the proteins. Under orders from President Gerald Ford, a vaccine was rushed into production and administered to 45 million Americans, at a cost of $135 million. The experimental vaccine of the University of Oxford and AstraZeneca are among the five potential candidates that have entered Phase III of human clinical trials. In animal studies, says Dr. James Baker, the company's chairman of the board, the spray protected 90% of mice from a lethal dose of influenza. (Blood cells would be fair game for the destructive emulsion, however, so the solution could not be injected into the body.) It had adopted a 70-year-old technique of injecting a flu virus into a fertilised hen’s egg. (The current seasonal flu vaccine would not be effective against the swine flu.) Yes, the vaccine to protect against the 2009 H1N1 influenza virus will be the same for the entire 2009-2010 influenza season, which extends into the spring of 2010.

(A VLP vaccine may also prove easier to develop since all it requires is an accurate genetic sequence of three critical virus genes. Here’s how it worksTorrent: Cut to ‘reduce’, revise fair value to Rs 2,350 a shareBudget 2020 hasn't violated fiscal discipline: FM SitharamanBudget 2020 was disappointing for lacking vision; but fiscal, taxation measures welcome: EAC-PM member Ashima GoyalBudget 2020: FM Nirmala Sitharaman says govt willing to do more beyond Union Budget to boost growthBudget 2020: FM says green shoots of recovery visible, points at worse macro-economic fundamentals under UPA Budget and the economy: What can we expect after this Budget?Budget 2020: FM Sitharaman takes on P Chidambaram over defence budget allocationBudget 2020 proposals on DDT, personal tax not to impact MF industry: Franklin TempletonBudget 2020: Chidambaram slams Modi govt; says economy close to collapse, unemployment making India poorerBudget 2020: How ESOP tax changes will benefit start-up employeesCopyright © (The SNS, maintained jointly by the Department of Homeland Security and the Department of Health and Human Services, is the nation's emergency medicine chest, containing critical drugs and medical equipment to be used in a public-health emergency.) Around the world, researchers are working on more than 165 potential Coronavirus vaccines, out of which around 27 have managed to reach the different stages of human trials. A doctor at the Centers for Disease Control examines specimens in an effort to develop new influenza vaccinesWith the first reported death from the 2009 H1N1 flu, or swine flu, in the U.S., the Federal Government and flu-vaccine manufacturers are preparing for the possibility that a new vaccine will be necessary to control the outbreak. That's because flu-vaccine production — whether for swine or seasonal flu — is time-consuming and laborious, requiring vaccine makers to grow millions of copies of the flu virus in chicken eggs, then purify those bugs into a ready-to-inject formula safe for patients. Genetic advances have given researchers entirely new ways of developing vaccines. We are on alert, waiting on the CDC. (Reuters image)COVID-19 vaccine In race against time vaccine developers look beyond conventional technologies Using this method, a vaccine for the 2009 H1N1 virus could be in production in 10 to 12 weeks, rather than the usual four to six months. "It provides the look and feel of the flu virus but does not have the genetic materials to cause disease," Singhvi says. We're in daily contact with them," says Donna Cary, spokeswoman for Sanofi Pasteur, which currently makes 50 million doses of the seasonal flu vaccine used in the U.S. each year.But if and when the CDC gives the go-ahead, companies such as Sanofi will have to do an about-face, scrapping their current vaccine projects to switch to swine flu. Around 90 per cent of yellow fever, measles, mumps, and influenza vaccines can be made from technology based on pathogen-free chicken egg, Chennai-based oncologist and vaccine specialist Anita Ramesh was quoted as saying by The Indian Express.However, the demand to develop a vaccine as early as possible has sidelined the traditional technology. 6 August 2009 | GENEVA - It takes approximately five to six months for the first supplies of approved vaccine to become available once a new strain of influenza virus with pandemic potential is identified and isolated. History teaches us, however, that it won't be easy. Nevertheless, Cary is confident: "We have two plants that both have the capability of producing what the U.S. market demand is for the seasonal and swine influenza vaccine," she says.

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